Almost 7 years ago, while going through some personal issues, I made a terrible mistake and ended up being convicted of driving under the influence (DUI) in the State of California. It was a dark period in my life, but I have moved on and learned my lesson. This spring, however, my intoxicated driving conviction […]
Preliminary testing by the Canadian Food Inspection Agency (CFIA) has confirmed the presence of H5 avian influenza on a duck farm near St. Catharines, Ontario as a low pathogenic subtype.
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“It is a crime against nature,” Jody Meche, president of the Louisiana Crawfish Producers Association-West, said while scanning the Bayou Bridge pipeline right-of-way on the west side of the Atchafalaya Basin, the country’s largest river swamp in a designated National Heritage Area.
His voice trembled with rage as he told me that he was speaking for all the animals living in the basin that can’t speak for themselves.
“The Bayou Bridge pipeline has left a dam across the Atchafalaya Basin affecting the fisheries, the birds, the otters, minks, raccoons, and nutria,” Meche said.
The Western Association of Broadcasters (WAB) plays a crucial role in educating your members on emerging issues in your industry.
Rare diseases, as the name suggests, have small patient populations. Historically, these were “orphaned” by the pharmaceutical industry- leaving few approved drug treatment options for those with these “orphan diseases.” An innovative project underway …
Under this new federal funding program, the governments of Canada and Quebec are investing $5,332,059 million in 5 water and wastewater projects to ensure residents of the Estrie region have access to clean and reliable water sources. Funding for these…
The Government of Canada is significantly increasing its investment, and expanding eligibility criteria to reduce injuries and fatalities, and increase public safety around the railway system.
Her Majesty’s Canadian Ship (HMCS) Charlottetown, while deployed on Operation REASSURANCE, will work and train in the Black Sea with vessels from several allied and partner nations from July 18 to August 2, 2016.
Canada and New Zealand share a common historical heritage and many current challenges including how the two justice systems serve their people.
Once again, I have no idea how “JOOOOOO!!!!”-y the comments can/will possibly be… INTJs account for an estimated 0.8 percent of the female population. We’re the rarest of the sixteen types, and having to share that distinction with Hillary takes some of the fun out of it. Then again, taking the fun out of things […]
The Honourable Stéphane Dion, Minister of Foreign Affairs, and the Honourable Harjit S. Sajjan, Minister of National Defence, each met today in Ottawa with Brett McGurk, Special Presidential Envoy for the Global Coalition to Counter ISIL, of the United States.
An uncompromising cinematic journey alongside the living and the dying inside Edmonton’s world-renowned Alberta Transplant Institute, the feature-length documentary Memento mori makes its hometown premiere at the Metro Cinema, on Thursday, November 10,…
Her Majesty’s Canadian Ship (HMCS) Vancouver returned to Canadian Forces Base (CFB) Esquimalt today after a successful six-month deployment.
Joe Bob Briggs writes: You’ve got the authoritarian reason, the idea that Trump voters want “a strong man like Putin.” Yeah, really? Would that be the same Scots-Irish people who followed John Knox, got kicked out of the Lowlands, caused all the ruckus in Ulster County, fought the Whiskey Rebellion in western Pennsylvania, and spread […]
The Honourable Navdeep Bains, announced a $700,000 investment to support the nomination process for the Klondike.
The Government of Canada is committed to restoring fair and balanced labour laws that recognize the important role of unions in Canada.
The governments of Canada and Ontario have announced funding for 35 projects in communities across the province under the New Building Canada Plan’s Small Communities Fund (SCF).
Congratulations to Dr. Michael Mann for successfully putting the boots to Winnipeg’s Frontier Centre for Public Policy. They defamed him; he fought back and won. See their grovelling apology below. Bask in their tears. &nbs…
When it comes to regulating pest control products, protecting the health and safety of Canadians and their environment is a priority for the Government of Canada.
Statement by Minister Joly on National Aboriginal Day
It is important that families experiencing separation or divorce have access to information, tools and services to help them make decisions and resolve issues in their children’s best interests.
Five United States (U.S.) residents on their way to visit Niagara Falls on July 2 were sent for a secondary examination where a revolver was discovered under the front passenger seat of the vehicle. Officers determined the 58-year old driver was inadmi…
Canada is experiencing a growing number of opioid overdoses and deaths across the country, and days such as the International Overdose Awareness Day are bringing needed attention to this crisis. The Government of Canada is committed to addressing this …
The Government of Canada delivered the first of two federal Gas Tax Fund installments for 2016-17 to all provinces and territories.
The Government of Canada is investing an additional $22 million in the restoration of the Fortifications of Québec National Historic Site and $15 million in the Québec Citadel for a total investment of $37 million in infrastructure.
The Honourable Stéphane Dion, Minister of Foreign Affairs, and the Honourable Marie-Claude Bibeau, Minister of International Development and La Francophonie, today issued the following statement regarding The Gambia’s presidential election.
Today, on the occasion of the Canadian Police and Peace Officers’ 39th Annual Memorial Service, flags on federal buildings across the country are flying at half-mast in honour of the more than 850 men and women whose names are engraved on the Honour Ro…
The Canadian Forces National Investigation Service (CFNIS) laid charges under the National Defence Act.
September 19, 2016 – Vancouver, British Columbia – Innovation, Science and Economic Development Canada – Post-secondary institutions help equip young Canadians with the education and training they need for future careers that will help them join a strong, healthy middle class.
Please allow me to begin by thanking our friend, His Excellency Tony Negus, for the warm reception he and his team at the [Australian] High Commission have put on this afternoon. I can think of no better occasion for our first meeting than to celebrate…
Last week saw the publication of an op-ed authored by Drs. David Ludwig, Cara Ebbeling, and Steven Heymsfield entitled, “Improving the Quality of Dietary Research“. In it they discuss the many limitations of dietary research and chart a way forward that includes the following 9 great suggestions,
But there was one recommendation that seems at odds with the rest,
Acknowledge that changes to, or discrepancies in, clinical registries of diet trials are commonplace, and update final analysis plans before unmasking random study group assignments and initiating data analysis.
For those who aren’t aware, clinical registries are where researchers document in advance the pre-specified methods and outcomes being studied by way of an observational experiment. The purpose of pre-registration is to reduce the risk of bias, selective reporting, and overt p-hacking that can (and has) occurred in dietary research.
Now to be clear, I’m a clinician, not a researcher, and I’m not sure how commonplace changes to or discrepancies in clinical registries of diet trials are, but I’m also not sure that’s an argument in their favour even if they are. I do know that recently two of the authors claiming registry changes are commonplace were found to have modified one of their pre-specified statistical analysis plans which if it had been adhered to, would have rendered their results non-significant.
But commonplace or not, is it good science?
To answer that question I turned to James Heathers, a researcher and self-described “data thug” whose area of interest is methodology (and who you should definitely follow on Twitter), who described the notion of accepting that changes and discrepancies to clinical registries were commonplace was, “deeply silly“.
He went on to elaborate as to why,
First of all – the whole definition of a theory is something which sets your expectations. the idea that ‘reality is messy’ does not interfere with the idea that you have hypothesis driven expectations which are derived from theories.
Second: there is nothing to prevent you saying “WE DID NOT FIND WHAT WE EXPECTED TO FIND” and then *following it* with your insightful exploratory analysis. In fact, that would almost be a better exposition of the facts by definition as you are presenting your expectations as expectations, and your after-the-fact speculations likewise.
Third: if you have a power analysis which determines there is a correct amount of observations necessary to reliably observe an effect, having the freedom to go ‘never mind that then’ is not a good thing by definition.
Fourth: The fact that changes were made is never ever included in the manuscript. i.e. they are proposing being able to make changes to the protocol in the registry *without* having to say so. it’s a ‘new plan’ rather than a ‘changed plan’.
Fifth: If you can still do the original analysis then no-one will ever believe that you didn’t change the plan after looking at the data. you have to protect yourself, and the best way to do that is to follow your own damned plans and be realistic from the get.
Lastly, Heathers is unimpressed with the argument that registry changes are A-OK because they’re commonplace, and he discussed ancient Aztecan punishments for those citing it.
All this to say, there’s plenty of room to improve the quality of dietary research. Here’s hoping the bulk of these suggestions are taken to heart, but please don’t hold your breath.
Cultural institution and museum in Shawinigan.
The Honourable Marc Garneau, Minister of Transport, will deliver a keynote address to the Greater Vancouver Board of Trade on January 25.
When the bombs rain down, Syria Civil Defence rushes in. In a place where public services no longer function, these unarmed volunteers risk their lives to help anyone in need-regardless of their religion or politics.
Connect with Nature at Fundy National Park’s Annual Christmas Bird Count
Today, the Honourable Carolyn Bennett, Minister of Indigenous and Northern Affairs, announced an investment of $3.15 million for the implementation of a five-year national strategy, the Path Forward 2016-2021. This includes a contribution from Innovation Science and Economic Development.
Good morning, everyone and thank you Marco. Thank you for graciously hosting us today in Lawrence Heights. It’s my pleasure to be here to talk about the future of Canadian communities. I would also like to recognize that we are on the traditional terri…
Members of the media are invited to attend an important infrastructure funding announcement with the Honourable Dominic LeBlanc, Minister of Fisheries, Oceans and the Canadian Coast Guard and Member of Parliament for Beauséjour, on behalf of the Honourable Amarjeet Sohi, Minister of Infrastructure and Communities; and the Honourable Brian Gallant, Premier of New Brunswick.
Ottawa, November 14, 2016-The Honourable Kirsty Duncan, Minister of Science, will be the keynote speaker at the 6th annual Mitacs Awards, which honour the work of outstanding participants in Mitacs’ research and training programs. Minister Duncan will …