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Diabetes

Disease Severity and Staging of Obesity

Posted October 15, 2014 by Arya M. Sharma, MD

Regular readers will be well aware of our work on the Edmonton Obesity Staging System (EOSS), that classifies individuals living with obesity based on how “sick” rather than how “big” they are. For a rather comprehensive review article on the issue of determining the severity of obesity and potentially using this as a guide to […]

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Diabetes

PHEN/TPM ER Improves Glycemic Control in Type 2 Diabetes

Posted October 10, 2014 by Arya M. Sharma, MD

The fixed combination of phentermine/topiramate extended release (PHEN/TMP ER), is marketed in the US as the anti-obesity drug Qsymia. Now a paper by Timothy Garvey and colleagues, published in Diabetes Care, describes the weight-lowering and anti-diabetic effect of this drug combination in individuals with type 2 diabetes. The investigators studied the effect of 56-week treatment […]

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Diabetes

Can Education Offset The Genetic Risk For Obesity?

Posted October 8, 2014 by Arya M. Sharma, MD

Obesity is a highly heritable condition with considerable penetrance, especially in our obesogenic enviroment. However, as I have pointed out before, having a genetic predisposition for obesity (like having a genetic predisposition for other diseases such as diabetes or high blood pressure) does not mean your fate is chiseled in stone. Lifestyle changes can significantly reduce […]

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